Virtual Physiology Lab

Medical experiment simulation software

Thomas RECORDING is the distributor of the “Virtual Physiology Lab” software tool for physiological and pharmacological experiments in virtual laboratories - almost like in the real world.

The simulation software is a platform independent tool developed by a group of experts from the University of Marburg (Germany). All stimulation and recording devices are freely adjustable. Mathematical algorithms guarantee for the appropriate reactions of the preparations, including their physiological diversity. 

Key features:

  • Realistic appearing, fully equipped laboratories on the computer screen
  • Simulates medical experiments almoste like in the real world
  • All stimulation and recording devices are freely adjustable
  • Mathematical algorithms guarantee for the appropriate reactions of the preparations, including their physiological diversity
  • SimNerve & SimMuscle feature classic physiological and pharmacological experiments with isolated preparations of the frog nerve and muscle
  • SimHeart & SimVessel allow classic experiments with rat heart and vessels
  • SimNeuron & SimNerve feature classical voltage and current clamp experiments

The Virtual Physiology series features classic physiological and pharmacological experiments with isolated preparations of the frog nerve and muscle (SimNerv©, SimMuscle©) and the rat heart and vessels (SimHeart©, SimVessel©), supplemented  by technically more challenging experiments like voltage- and patch-clamp recordings (SimNeuron©, SimPatch©), that are unfeasible to be physically carried out in students’ introductory  courses but can be realized in silico with a user-friendly interface.

Ordering Information

We offer up to 6 product licences. You can combine the programs that you would like to use in your lab and choose the required license. For example you want to use SimNerve© and SimNeuron© you need a 2-program license.

SimHeart©

Figure 1: Screenshot of SimHeart©

SimHeart© allows to make experiments with diverse transmitters and drugs applied to the isolated heart in the classical Langendorff set-up

SimMuscle©

Figure 2: Screenshot of SimMuscle©

SimMuscle© allows recordings of skeletal muscle contractions under different stimulus conditions and pre-stretchings in a new, resolution independent laboratory.

SimNeuron©

Figure 4: Screenshot of SimNeuron©

SimNeuron© simulates virtual current- and voltage-clamp labs for recordings of membrane potentials and ion currents, including diverse single channel applications.

SimNerve©

Figure 3: Screenshot of SimNerve©

Sim Nerve© is a virtual laboratory for compound action potential recordings from the frog sciatic nerve under freely adjustable stimulus conditions. Download a demo version of the completely revised laboratory with several new features and have a look on suggested experiments, described in the tutorial and protocol forms, including registrations.

SimVessel© - coming soon

Figure 5: Screenshot of SimVessel©

SimVessel© allows the examination and comparison of drug effects on smooth muscles of vessels (aorta) and the intestine (antrum) in a virtual laboratory.

This product is not yet available.

Publications

[3] Aubin Tchaptet, Svetlana Postnova, Christian Finke, Horst Schneider, Martin T. Huber, Hans A. Braun Modeling neuronal activity in relation to experimental voltage-/patch-clamp recordings Brain Research 1536 (2013) 159 – 167, dx.doi.org/10.1016/j.brainres.2013.06.029

[2] The Real and Virtual Laboratory: A Conversation with Dr. Hans Braun The Newsletter of the Division of Biological Physics of the American Physical Society, Vol.1 No.1 June 2001, p 5-7

[1] Hans A. Braun Virtual versus real laboratories in life science education: Concepts and experiences. Guinea Pig to Computer Mouse, Eds.: Nick Jukes & Mihnea Chiuia, InterNICHE 2003, pp81 - 87

 

 

 

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