Screw Microdrive System without preamplifier

1-Channel System / 4-Channel System

Key features:

  • Reusable Microdrive system
  • Electrode travel range up to 8.000µm
  • Small and lightweight
  • No electrode connection cables free in air! Complete metal shield around all microelectrodes
  • Suitable for cortical and deep brain recordings
  • Stable long-term recordings with thin microelectrodes for hours
  • Integrated 4 channel low noise preamplifier
  • Electrode movement by screw turning
  • Multichannel commutator (swivel) optional for freely moving applications optional available

Figure 1: Tetrode Screw drive (TSD-02) mounted on an implantable titanium base plate

The reusable tetrode screw drive (1) in figure 1 is mounted on an implantable titanium base plate (2). The Tetrode Screw Drive is equipped with an integrated 4 channel preamplifier. 

Figure 2: Tetrode screw drive (TSD-2) with integrated 4 channel preamplifier mounted on a rat.

This device is intended to be used in chronic long term recording applications with freely moving rats (see figure 2). A screw driver is used to move the tetrode or single electrode up and down. The preamplifier output cable is connected to a battery power supply and a main amplifier with a thin connection cable via slip ring commutator (see figure 3) which is optional available from Thomas RECORDING. 

Figure 3: Tetrode screw drive on a freely moving rat

The tetrode screw device (TSD-2) consists of the following components (see figure 4): 

Tetrode Screw Drive components (1) depth control for electrode with millimeter scale, (2) implantable titanium base plate, (3) tetrode screw drive guide tube, (4) metal housing for screw drive and integrated 4 channel preamplifier, (5) screw

Figure 4: Tetrode Screw Drive components (1) depth control for electrode with millimeter scale, (2) implantable titanium base plate, (3) tetrode screw drive guide tube, (4) metal housing for screw drive and integrated 4 channel preamplifier, (5) screw

The Thomas tetrode screw drive moves a quartz glass insulated platinum-tungsten electrode which is shown in figure 5. The tetrode has 4 independent metal cores and an outer diameter of 100µm. Tetrodes have some advantages in comparison to single electrodes. Hargreaves et al. have tested Thomas tetrodes in comparison to FHC single electrodes and reported the results The authors did evaluate the advantages of tetrode recordings, and examined if there were any differences in terms of yield, time, and the neuronal types that could be acquired. 

(A) Tetrode tip, (B) Tetrode cross section, (C) Tetrode signals

Figure 5: (A) Tetrode tip, (B) Tetrode cross section, (C) Tetrode signals

If the screw drive is mounted to the animal´s skull the tetrode can be moved up and down by turning the screw with a screw driver. Currently we plan to offer a motor unit that one can mount on the screw drive to drive the tetrode software controlled.

Figure 6: The tetrode can be moved up and down by turning the screw with a screw driver clockwise or counter clockwise.


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