Alexandre Mourot, PhD
Alexandre Mourot is a tenured researcher in the department of Neurobiology of Adaptive Processes at the Université Pierre et Marie Curie in Paris/France.
Alexandre about his research
My lab is interested in the circuits underlying nicotine addiction. We are using a combination of ex- and in-vivo electrophysiology, house-developed optogenetic tools and behavioral assays in mice to understand the molecular and cellular adaptations triggered by chronic nicotine, and the consequences at the behavioral level. We focus on two main addiction pathways: the midbrain dopamine system and the habenulo-interpeduncular pathway, which are involved in nicotine reinforcement and aversion, respectively.
We are developing technologies for the optogenetic control of brain receptors and ion channels in the behaving mouse.