Ceramic Screw – SI BRAIN PORT
MRI- and bio-compatible miniature brain port
Ceramic Screw – SI BRAIN PORT
MRI- and bio-compatible miniature brain port
For MRI applications care must be taken to limit the amount of magnetically susceptible metal inside the MRI scanner. The TREC “SI BRAIN PORT” uses a ceramic screw type SI with a center hole for easy access to the brain, the use of ceramic material limits the distortion caused to the MRI scan.
- Port to the brain via center hole
- Easy to implant
- MRI-compatible
- Material: ceramic
- No dura scraping required
- Reduced risk for infection
Features
Ceramic screw with a center hole, working as an easy to use brain port. You can use the screw as a port for easy access to the brain for chronic or acute neurophysiological applications. One or several screws can be used. 3 step implantation process is very easy. Use our special designed ceramic screw tools andto:
- Drill a hole into the skull
- Cut a thread into the bone
- Screw the ceramic screw in
Port is immediately ready for use for:
- Insert a Microdrive guide tube through the hole to make acute cortical or deep brain recordings
- Insert a microelectrode through the hole and fix the electrode to the screw for chronic recordings
- Insert an injection cannula trough the hole to inject a drug
- Insert an optical fiber through the hole to stimulate neurons with light
- Insert an electrical stimulation electrode through the hole for electrical stimulation
etc.
The screw is a port to the brain that has many advantages:
- It is easy and fast to implant without craniotomy
- It does not require regular dura scraping as it is for implantable recording chambers
- It reduces the risk of infection in comparison to large craniotomies. Use several single screws with a hole to cover a larger brain area.
- The port to the brain allows to use different neurophysiological techniques. (e.g. Thomas MEM drive, etc)
- Place the screw exactly above the brain target based on MRI or CT scans by using 3D-neuronavigation system (available from our company)
High reproducibility of lateral recording/stimulation position
Downloads
Publications
[13] Dougherty, K., Carlson, B. M., Cox, M. A., Westerberg, J. A., Zinke, W., Schmid, M. C., … & Maier, A. (2021). Binocular suppression in the macaque lateral geniculate nucleus reveals early competitive interactions between the eyes. Eneuro.
[12] Lee S.-K., Hwang S.-H., Barg J.-S., Yeo S,.J. Rapid, theoretically artifact‐free calculation of static magnetic field induced by voxelated susceptibility distribution in an arbitrary volume of interest. March 2018, DOI: 10.1002/mrm.27161
[11] Srivatsun Sadagopan, Wilbert Zarco, Winrich A Freiwald, A causal relationship between face-patch activity and face-detection behavior. eLIFE Sciences, April 2017, DOI: 10.7554/eLife.18558
[10] Karolina Marciniak, Artin Atabaki, Peter W Dicke, Peter Thier, Disparate substrates for head gaze following and face perception in the monkey superior temporal sulcus. eLIFE Sciences, July 2014
[9] Melanie Wilke, Igor Kagan, Richard A. Andersen, Functional Imaging Reveals Rapid Reorganization of Cortical Activity after Parietal Inactivation in Monkeys. Proceedings of the National Academy of Sciences of the United States of America ( PNAS ), May 2012 (please see supporting information)
[8] Joseph Feingold, Theresa M. Desrochers, Naotaka Fujii, Ray Harlan, Patrick L. Tierney, Hideki Shimazu, Ken-ichi Amemori, Ann M. Graybiel, A system for recording neural activity chronically and simultaneously from multiple cortical and subcortical regions in nonhuman primates. Journal of Neurophysiology, December 2011
[7] Mark S. Bolding, Meredith A. Reid, Kathy B. Avsar, Rosalinda C. Roberts, Paul D. Gamlin, Timothy J. Gawne, David M. White, Jan A. den Hollander, Adrienne C. Lahti, Magnetic Transfer Contrast Accurately Localizes Substantia Nigra Confirmed by Histology. Biological Psychology, July 2012
[6] Anil Bollimunta and Jochen Ditterich, Local Computation of Decision-Relevant Net Sensory Evidence in Parietal Cortex. Cerebral Cortex, April 2012
[5] Elias B. Issa, James J. DiCarlo, Precedence of the Eye Region in Neural Processing of Faces. Journal of Neuroscience, November 2012
[4] Alexander Maier, Christopher J. Aura, David A. Leopold, Infragranular Sources of Sustained Local Field Potential Responses in Macaque Primary Visual Cortex. Journal of Neuroscience, February 2011
[3] Alexander Maier, Geoffrey K. Adams, Christopher Aura, David A. Leopold, Distinct superficial and deep laminar domains of activity in the visual cortex during rest and stimulation. frontiers in Systems Neuroscience, August 2010
[2] Scherberger H., Fineman I., Musallam S., Dubowitz D.J., Bernheim K.A., Pesaran B., Corneil B.D., Gilliken B., Andersen R.A., Magnetic resonance image-guided implantation of chronic recording electrodes in the macaque intraparietal sulcus. Journal of Neuroscience Methods 130 (2003) 1-8
[1] Logothetis N., Guggenberger H., Peled S., Pauls J., Functional imaging of the monkey brain. nature neuroscience, vol. 2 no. 6, June 1999
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